商品名：Cardizem and Dilacor
Calcium-channel blocking drug. Diltiazem blocks calcium entry into cells via blockade of voltage-dependent slow calcium channel. Via this action, it produces Diltiazem Hydrochloride 235 D vasodilation, negative chronotropic effects, and negative inotropic effects. However, the action on cardiac tissue (SA node and AV node) predominates over other effects. Half-life in dogs is approximately 3 hours (range 2.5-4 hrs), and it is shorter in horses (1.5 hrs).
Diltiazem is used primarily for control of supraventricular arrhythmias, systemic hypertension, and hypertrophic cardiomyopathy. It also is used for atrial flutter, AV nodal re-entry arrhythmias, and other forms of tachycardia. Diltiazem is more effective on heart tissues (AV node and SA node) than on blood vessels. It should not be used as a primary treatment of hypertension and to produce vasodilation; one of the dihydropyridines calcium-channel blocking drugs (e.g., amlodipine) is preferred. In cats it is considered one of the drugs of choice for treatment of feline hypertrophic cardiomyopa
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
先確認所在地法規、精確產品、劑型、有效成分強度基準與目前授權狀態。 確認動物種類、心律問題、心臟結構、血壓、傳導狀態、肝腎功能與所有同時用藥。 愛爾蘭有效授權不代表目前可供應；法國與北愛爾蘭狀態不可互相套用。 人用標籤、歷史產品資料、研究暴露與藥動數值不得直接轉成通用處方或計算器輸入。 疑似過量、昏厥、明顯虛弱、呼吸困難或心搏異常必須立即由獸醫師評估。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
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