商品名：Tagamet (OTC and prescription)
Histamine2 antagonist (H2 blocker). Stimulation of acid secretion in the stomach requires activation of histamine type 2 receptors, gastrin receptors, and muscarinic receptors. Cimetidine and related H2 blockers inhibit the action of histamine on the histamine H2 receptor of parietal cells and inhibit gastric parietal cell gastric acid secretion. Cimetidine increases stomach pH to help heal and prevent gastric and duodenal ulcers.
Cimetidine is used to treat gastric ulcers and gastritis. Although it is often used for animals with vomiting, there are no efficacy data to indicate that it is effective. There also are no efficacy data to support its use for preventing nonsteroidal anti-inflammatory drug (NSAID)–induced bleeding and ulcers. In dogs, clinical efficacy is limited and other drugs (e.g., famotidine, ranitidine, and proton-pump inhibitors) are preferred for ulcer treatment. In horses, cimetidine has been used to prevent or treat GI ulcers. However, the efficacy for these indications has not been proved. For examp
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現行犬貓、馬、犢牛、腎衰、免疫調節與錠劑換算列混合臨床指引、PK／研究與人用產品；需完成適應症、cimetidine-equivalent、route、腎肝、交互作用、療程與法規 gate。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
1.3 hours
renal