商品名：Zantac
Histamine2 antagonist (H2 blocker). Ranitidine, like other H2 blockers, suppresses histamine stimulation of gastric parietal cell to decrease gastric acid secretion. Ranitidine will increase stomach pH. Ranitidine is longer acting and 4 to 10 times more potent than cimetidine. The half-life of ranitidine is longer than cimetidine, which results in decreased frequency of administration for ranitidine. When adjusting doses, ranitidine hydrochloride is 89% ranitidine.
Ranitidine is used to treat ulcers and gastritis. It does not produce as much of a sustained increase in stomach pH as proton pump inhibitors (omeprazole). Ranitidine (6.6 mg/kg PO) in foals suppressed acid for 6 hours, but omeprazole suppressed acid for 22 hours at 4 mg/kg. It is used to prevent nonsteroidal anti-inflammatory drug (NSAID)–induced ulcers in animals, although efficacy has not been demonstrated for this effect. In horses, ranitidine did not improve healing of ulcers induced by NSAIDs, and it was not as effective as omeprazole for treating ulcers. Ranitidine may stimulate stomach
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確切產品、法域、劑型、途徑、ranitidine 活性部分／hydrochloride 鹽基準、物種、適應症、腎功能與療效終點全部確認前，不得產生處方或回退舊劑量。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
81%
2.2 hours
renal