商品名:Lysovir*, Symmetrel*
Neutralizes gastric hydrochloric acid. May also bind bile acids and pepsin and stimulate local prostaglandin (PGE-1) production. Also binds inorganic phosphate (PO43–) in the GI tract, making it unavailable for absorption.
Management of gastritis and gastric ulceration. In renal failure, to lower serum phosphate levels in cats and dogs with hyperphosphataemia. Frequent administration is necessary to prevent rebound acid secretion. Phosphate-binding agents are usually only used if low-phosphate diets are unsuccessful. Monitor serum phosphate levels at 10–14 day intervals and adjust dosage accordingly if trying to normalize serum concentrations. Thoroughly mix the drug with food to disperse it throughout the GI trac
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
先核對確切鋁鹽、具名產品、濃度與完整配方,禁止在氫氧化鋁、碳酸鋁、磷酸鋁或人用鋁鎂複方間自動換算。 確認物種、體重、用途、慢性腎病分期、血磷與鈣、餐食磷含量、排便狀況、神經肌肉狀態、血球指標及所有併用藥物。 磷結合用途須依飲食與血磷反應個別調整;制酸用途須先確認具名產品與適應症,磷酸鋁制酸產品不得誤當食物磷結合劑。 若出現新發無力、顫抖、步態異常、意識改變或小球性變化,應評估鋁累積並考慮改用不含鋁的替代方案。 妊娠、哺乳、食用動物、其他物種及任何自動交互作用均須另行完成證據與法規審查。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。