商品名：Gabapetin, Neurontin, and generic brands
Anticonvulsant and analgesic. Gabapentin is an analogue of the inhibitory neurotransmitter GABA; however, it is not an agonist or antagonist for the GABA receptor. The mechanism of anticonvulsant action and analgesic effects is not clear, but there is evidence that the mechanism of action appears to be via blocking calcium-dependent channels. Gabapentin inhibits the alpha-2-delta (α2 δ) subunit of the N-type voltage-dependent calcium channel on neurons. Via inhibition, it reduces calcium influx that is needed for release of neurotransmitters—specifically, excitatory amino acids—from presynapti
Gabapentin is used as an anticonvulsant and to treat chronic pain syndromes, including neuropathic pain. It is used to treat neuropathic pain that does not respond to nonsteroidal anti-inflammatory drugs (NSAIDs) or opiates. However, studies demonstrating efficacy for pain treatment in dogs and cats are currently lacking. When used to treat epilepsy, it (or pregabalin) is usually considered when the seizures have become refractory to other drugs. Clinical efficacy studies in veterinary medicine are lacking for either use, and treatment regimens have been mostly derived from anecdotal evidence
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
腎功能調整：Reduce dose in renal impairment. In humans gabapentin is ~100% renally eliminated; in dogs ~30-40% is metabolized so mild-to-moderate canine renal dysfunction may not require dose adjustment. Severe renal impairment in any species: reduce dose.
腎功能調整：Reduce dose in renal impairment. In humans gabapentin is ~100% renally eliminated; in dogs ~30-40% is metabolized so mild-to-moderate canine renal dysfunction may not require dose adjustment. Severe renal impairment in any species: reduce dose.
在確認精確產品／active concentration／賦形劑與犬用 xylitol-free、物種、體重、適應症／目標、route、腎功能、CNS depressant 與呼吸風險、癲癇／taper 脈絡及監測／複評計畫前，封鎖通用計算；研究時程只保留為不可執行證據。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
80%
2-4 hours