商品名：Capoten
ACE inhibitor. Captopril inhibits conversion of angiotensin I to angiotensin II, leading to vasodilation. Angiotensin II is a potent vasoconstrictor and will stimulate sympathetic stimulation, renal hypertension, and synthesis of aldosterone. ACE inhibitors limit the ability of aldosterone to cause sodium and water retention that contribute to congestion. Captopril, like other ACE inhibitors, will cause 100 Captopril vasodilation, but ACE inhibitors also contribute to vasodilation by increasing concentrations of some vasodilating kinins and prostaglandins.
Captopril, like other ACE inhibitors, is used to treat hypertension and CHF. It has been used primarily in dogs, but its use has declined. Captopril is the first ACE inhibitor available for clinical use but has been replaced by other ACE inhibitors such as enalapril, benazepril and lisinopril. Unlike benazepril and enalapril, it has not been studied for clinical use in dogs and cats.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
須確認犬／貓、心衰分期或重複量測的高血壓／蛋白尿診斷、實際單方產品、灌流／水合、BP、creatinine、potassium 與全部利尿／血管擴張／NSAID／RAAS 共用藥後，才由獸醫選 regimen；因此通用 calculator、處方與飼主劑量封鎖。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。