商品名:Prilium
Angiotensin converting enzyme (ACE) inhibitor. It inhibits conversion of angiotensin I to angiotensin II and inhibits the breakdown of bradykinin. Overall effect is a reduction in preload and afterload via venodilation and arteriodilation, decreased salt and water retention via reduced aldosterone production and inhibition of the angiotensin- aldosterone-mediated cardiac and vascular remodelling. Efferent arteriolar dilation in the kidney can reduce intraglomerular pressure and therefore glomeru
Treatment of congestive heart failure caused by mitral regurgitation or dilated cardiomyopathy in dogs and cats. Often used in conjunction with diuretics when heart failure is present as most effective when used in these cases. Can be used in combination with other drugs to treat heart failure (e.g. pimobendan, spironolactone, digoxin). May be beneficial in cases of chronic renal insufficiency, particularly protein-losing nephropathies. May reduce blood pressure in hypertension. ACE inhibitors a
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現有犬貓計算劑量錯誤。Prilium 三種規格的復溶濃度與最低體重不同;在系統能強制犬、法域、心衰適應症、確切規格、最低體重、血壓、腎功能、電解質與處方者審核前,封鎖自動計算與飼主劑量。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。