商品名:Lotensin (human preparation) and Fortekor,
ACE inhibitor. Inhibits conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor and will also stimulate sympathetic stimulation, renal hypertension, and synthesis of aldosterone. The inhibition of aldosterone will decrease sodium and water retention. Benazepril, like other ACE inhibitors, will produce vasodilation and decrease aldosterone-induced congestion. ACE inhibitors also contribute to vasodilation by increasing concentrations of some vasodilating kinins and prostaglandins. Unlike enalapril, benazepril has a dual mode of elimination through the kidneys a
Benazepril, like other ACE inhibitors, is used to treat hypertension and CHF. Evidence shows that it may decrease the likelihood of developing cardiomyopathy in some dogs, but other studies failed to show this benefit. For treatment of occult mitral valve disease in dogs, there has not been a benefit of therapy. It may benefit some cats in heart failure or with systemic hypertension; however, some cats with hypertension may not respond, and ACE inhibitors are not considered a primary treatment for hypertension in cats. Benazepril has limited antihypertensive effects in cats with naturally occu
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
執行前必須由獸醫師完整確認精確產品與鹽基強度、犬或貓、診斷與疾病分期、給藥途徑、個體狀態、腎功能與水合、血壓與電解質、所有併用藥、監測計畫及法域。任一項未閉合時,不得輸出劑量、計算、處方或飼主數值指示。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal