商品名：Enacard (veterinary preparation) and Vasotec (human
ACE inhibitor. Like other ACE inhibitors, it inhibits conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor and will also stimulate sympathetic stimulation, renal hypertension, and synthesis of aldosterone. The ability of aldosterone to cause sodium and water retention contributes to congestion. Enalapril, like other ACE inhibitors, will cause vasodilation and decrease aldosterone-induced congestion, but ACE inhibitors also contribute to vasodilation by increasing concentrations of some vasodilating kinins and prostaglandins.
Enalapril, like other ACE inhibitors, is used to treat hypertension and CHF. Efficacy for CHF is good and can be used with other drugs such as pimobendan, furosemide, digoxin, and spironolactone. It is primarily used in dogs. In addition to its use for treatment of congestive heart failure, enalapril has been used to delay onset of CHF in dogs with mitral regurgitation. The benefit of enalapril and other ACE inhibitors for occult heart disease is controversial; some studies have shown a benefit and others have not. Enalapril has been used in some cats in heart failure or with systemic hyperten
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
腎功能調整：Start at lower dose; monitor creatinine and K+
腎功能調整：Start at lower dose; monitor creatinine and K+
腎功能調整：Start at lower dose; monitor creatinine and K+
腎功能調整：Start at lower dose; monitor creatinine and K+
有症狀 CHF、犬持續性腎蛋白尿與貓 off-label adjunct 的證據層級不同；通用計算器缺少 hydration、BP、腎功能、鉀、利尿與 dual-RAAS 閘門，並混入未證實物種／適應症。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。