商品名：Banamine and generic brands
Flunixin is an NSAID. Flunixin and other NSAIDs produce analgesic and anti- inflammatory effects by inhibiting the synthesis of prostaglandins. The enzyme inhibited by NSAID is the cyclo-oxygenase (COX) enzyme. The COX enzyme exists in two isoforms: COX-1 and COX-2. COX-1 is primarily responsible for synthesis of prostaglandins important for maintaining a healthy GI tract, renal function, platelet function, and other normal functions. COX-2 is induced and responsible for synthesizing prostaglandins that are important mediators of pain, inflammation, and fever. However, it is known whether there is some crossover of COX-1 and COX-2 effects in some situations, and COX-2 activity is important for some biological effects. Flunixin is not selective for either COX-1 or COX-2. Other anti- inflamm
Flunixin is used primarily for short-term treatment of moderate pain and inflammation. It has been used to treat abdominal pain in horses, to decrease signs of sepsis in horses, and to decrease clinical signs associated with coliform mastitis in cattle. In horses, as an adjunctive treatment for sepsis, it is used at a low dose of 0.25 mg/kg. It has been used as an adjunctive treatment, with antibiotics, for treatment of bovine respiratory disease (BRD). Flunixin has been combined with antibiotics for treatment of BRD (e.g., florfenicol in Resflor) in which it reduces inflammatory lung reactions. Flunixin has been used as a single dose for treatment of diarrhea in dairy calves. Flunixin at 2.2 mg/kg IV in cows with endotoxin mastitis did not affect milk production, but it decreased fever an
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
未確認精確產品、法域、物種、flunixin-equivalent 規格、途徑／部位、適應症、期間／重複規則、水合／灌流、GI／腎／肝／止血風險、生殖狀態、共同用藥及肉／乳放行日期前，封鎖所有通用計算。犬、貓、雪貂與鳥不得計算。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
80%