商品名：Zeniquin and Marbocyl (European name)
Fluoroquinolone antimicrobial. Marbofloxacin acts via inhibition of DNA gyrase in bacteria to inhibit DNA and RNA synthesis. Marbofloxacin is a bactericidal with a broad spectrum of activity. Sensitive bacteria include Staphylococcus, Escherichia coli, Proteus, Klebsiella, and Pasteurella. Pseudomonas aeruginosa is moderately sensitive but requires higher concentrations. Some methicillin-resistant Staphylococcus also may be resistant to fluoroquinolones. Marbofloxacin has poor activity against streptococci and anaerobic bacteria.
Marbofloxacin, like other fluoroquinolones, is used to treat susceptible bacteria in a variety of species. Marbofloxacin is registered for use in dogs and cats. Infections treated with marbofloxacin include skin and soft tissue infections, bone infections, UTIs, pneumonia, and infections caused by intracellular organisms. Marbofloxacin has been effective for some bloodborne pathogens such as Mycoplasma haemofelis, in cats at a dose of 2.75 mg/kg q24h PO for 14 days. Marbofloxacin also has been used in horses to treat infections caused by susceptible bacteria. In dogs the half-life is 7-9 hours
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認 marbofloxacin 母體身分、精確品牌、成品、濃度或錠劑強度、賦形劑、容器、製造商、批次、法域及當期核准與實際供應。 確認病患物種、品種、年齡、體重、生長與繁殖狀態、食用動物及生產類別、精確感染部位、嚴重度、病原、培養與感受性。 核對腎、肝、水合、神經、癲癇、關節、過敏史及所有藥物、礦物補充品與共同處置。 依精確成品與病患核對數值基礎、途徑、頻率、時程、停用與再評估規則、禁忌、監測、救援及轉診條件；母體資料不得產生數值。 十六個保護 peer 均須人工雙向裁決；標示提醒、類別理論、同篇出現或小型藥動學命中不得自動化。 若屬食用動物，須依法域核對精確成品、生產類別、適應症與停藥期；不得由別成品或別法域推算。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
94%
9-12 hours