商品名:Macrodantin, Furalan, Furatoin, Furadantin, and
Antibacterial drug. Urinary antiseptic. Therapeutic concentrations are reached only in the urine. In the urine it is reduced by bacterial flavoproteins, and the reactive metabolites inhibit bacterial macromolecules (DNA and RNA). Resistance among bacteria is unusual, although Proteus and Pseudomonas aeruginosa are inherently resistant. Macrocrystalline form is slowly absorbed and less likely to cause gastric upset. Microcrystalline form is rapidly absorbed in intestine. animals even at 8 weeks of age. Some transient pruritus may occur shortly after administration, which coincides with the initial killing of fleas. Contraindications and Precautions Do not use in dogs or cats <1 kg (2 pounds) in weight. Do not use in cats or dogs younger than 4 weeks of age. Drug Interactions No drug interac
Nitrofurantoin is administered orally for treatment or prevention of UTIs. It does not attain high enough concentrations for systemic infections or kidney infections. Although it is used in animals for UTI, the use in animals has been primarily derived from empirical use or from experience in humans. There are no well-controlled clinical studies or efficacy trials to document clinical effectiveness.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現行服務在缺少感染部位、培養、產品、腎功能/尿量與監測 gate 時仍輸出 q6h、反覆 UTI 及腎功能異常計算;馬用與常規 q24h 預防亦不應作通用方案。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。