商品名:Lasix and generic brands
Furosemide is a loop diuretic that inhibits the Na+/K+/2Cl- cotransporter in the ascending thick loop of Henle. It is often called high-ceiling diuretics because it is more effective than other diuretics. Furosemide decreases the sodium, chloride, and potassium reabsorption from the tubule. Subsequently, these ions are retained in the renal tubule and presented to the distal nephron. Dilute urine is produced because water is retained in the tubule when it reaches the distal tubule. In addition, there is an associated urine loss of Mg++ and Ca++. An additional mechanism of action is via prostag
In small animals, furosemide is the drug of choice to treat conditions that cause edema: pulmonary edema, liver disease, heart disease, and vascular disease. It increases urine production and can be used to treat acute renal failure. In addition, furosemide will increase K+ and Ca++ excretion and is used to treat hyperkalemia and hypercalcemia. In horses, furosemide has been used to treat edema and syndromes associated with congestion. The most common use in horses is pretreatment prior to racing. Although it appears to produce faster racing times, the mechanism is unclear. It may decrease bod
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
腎功能調整:In acute oliguric renal failure, escalate stepwise (2 then 4 then 6 mg/kg IV) if diuresis does not develop; monitor electrolytes (especially K+) and hydration closely.
腎功能調整:In acute oliguric renal failure, escalate stepwise (2 then 4 then 6 mg/kg IV) if diuresis does not develop; monitor electrolytes (especially K+) and hydration closely.
確認活性本體、商品、鹽型、濃度、劑型與實際標籤。 確認物種、體重、診斷、急慢性病程、照護場域與治療目標。 評估水合、灌流、血壓、腎功能、電解質、尿量、聽覺風險與合併用藥。 若為產食動物或競賽馬,核對當地現行產品標籤與規則。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
77%
1-1.5 hours