Like other NSAIDs, ketorolac exhibits analgesic, antiinflammatory, and antipyretic activity probably through its inhibition of cyclooxygenase with resultant impediment of prostaglandin synthesis. Ketorolac may exhibit a more potent analgesic effect than some other NSAIDs. It inhibits both COX-1 and COX-2 receptors.
Ketorolac is used primarily for its analgesic effects for short-term treatment of mild to moderate pain in dogs and rodents. The duration of analgesic effect in dogs is about 8 – 12 hours, but because of the availability of approved, safer NSAIDs for dogs, its use is questionable.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
腎功能調整：Contraindicated in patients with renal impairment or a history of renal disease.
肝功能調整：Avoid in patients with hepatic impairment or a history of hepatic disease.
腎功能調整：Contraindicated in patients with renal impairment or a history of renal disease.
肝功能調整：Avoid in patients with hepatic impairment or a history of hepatic disease.
公開犬貓資料主要是單次、藥動或特定眼用研究，不能支持現行 q8–12h 重複系統給藥。核心外用劑型與系統劑量亦衝突；拆分途徑並經獸醫藥理審核前禁止計算。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
50-75%
4-8 hours
renal