商品名:Daranide
Carbonic anhydrase inhibitor. Diuretic. Dichlorphenamide, like other carbonic anhydrase inhibitors, produces a diuresis by inhibiting the reabsorption of bicarbonate in proximal renal tubules via enzyme inhibition. This action results in loss of bicarbonate in the urine and a diuresis. The action of carbonic anhydrase inhibitors results in significant urine loss of bicarbonate, alkaline urine, and water loss.
Dichlorphenamide is rarely used as a diuretic any longer. There are more potent and effective diuretic drugs available such as the loop diuretics (furosemide). Dichlorphenamide, like other carbonic anhydrase inhibitors, is used primarily to reduce intraocular pressure in animals with glaucoma. Methazolamide is used more often than dichlorphenamide or acetazolamide for this purpose, and other treatment regimens are used more often than carbonic anhydrase inhibitors. Dichlorphenamide, like other carbonic anhydrase inhibitors, is sometimes used to produce a more alkaline urine for management of some urinary calculi.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
先確認英文成分 Dichlorphenamide,禁止把核心中文名稱醋甲唑胺或 Methazolamide 當作同義詞。 確認原廠產品、有效成分、鹽型、濃度、劑型、動物種類、體重、診斷、青光眼分類與眼壓狀態。 由獸醫師依腎臟、肝臟、呼吸、酸鹼與電解質狀態、過敏史、生殖狀態及完整併用藥決定是否可用。 另行建立明確的種別、產品、適應症、給藥途徑、劑量、頻率、療程、監測、停藥與緊急處置契約後才可執行。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。