商品名:Diamox
Carbonic anhydrase inhibitor. Acetazolamide, like other carbonic anhydrase inhibitors, produces a diuresis through inhibition of the uptake of bicarbonate in proximal renal tubules via enzyme inhibition. This action results in loss of bicarbonate in the urine and a diuresis. The action of carbonic anhydrase inhibitors results in urine loss of bicarbonate, alkaline urine, and water loss.
Acetazolamide is rarely used as a diuretic any longer. There are more potent and effective diuretic drugs available such as the loop diuretics (furosemide). Acetazolamide, like other carbonic anhydrase inhibitors, is used primarily to lower intraocular pressure in animals with glaucoma. Methazolamide is used more often than acetazolamide for this purpose, and other treatment regimens are now used more often than carbonic anhydrase inhibitors. Acetazolamide, like other carbonic anhydrase inhibitors, is sometimes used to produce more alkaline urine for management of some urinary calculi.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
公開證據同時包含現行特定美國犬用產品法規、獸醫參考敘述、小型研究、單一犬過量病例及人用標示;尚不足以安全建立跨產品、跨物種、跨用途的自動執行資料。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)