Meloxicam has antiinflammatory, analgesic, and antipyretic activity similar to other NSAIDs. Like other NSAIDs, meloxicam exhibits analgesic, antiinflammatory, and antipyretic activity probably through its inhibition of cyclooxygenase, phospholipase A2, and inhibition of prostaglandin synthesis. It is considered COX-2 preferential (not COX-2 specific) as at higher dosages its COX-2 specificity is diminished. Acute dosing studies in dogs have not demonstrated any untoward renal or hepatic toxicity.
Meloxicam is principally used for the symptomatic treatment of osteoarthritis in dogs. Short-term (single dose injectable) use is also approved (in the USA) for cats for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration when administered prior to surgery.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
腎功能調整:Avoid or use with extreme caution in renal impairment
腎功能調整:Avoid or use with extreme caution in renal impairment
腎功能調整:Avoid or use with extreme caution in renal impairment
腎功能調整:Avoid or use with extreme caution in renal impairment
腎功能調整:Avoid or use with extreme caution in renal impairment
確認原包裝精確商品、法域、濃度、劑型、包裝、量測工具與開封時間 確認物種、年齡、體重、適應症、途徑、既往 meloxicam 或其他 NSAID 暴露與是否為手術情境 評估水合、血容量、血壓、腎肝心功能、GI 病史、出血疾病、繁殖狀態與全部合併用藥 建立完整病史與理學檢查、血液學與血清生化 baseline、後續檢驗、療效與停藥就醫條件 美國貓用單次注射與英國或臺灣貓用口服產品永久分流;不得跨法域轉移給藥或保存規則
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
15 hours
fecal