商品名:Apresoline
Vasodilator. Antihypertensive. Hydralazine relaxes vascular smooth muscle and reduces blood pressure. In arteriolar vascular beds it relaxes vascular smooth muscle to reduce vascular resistance and improves cardiac output. The mechanism of action is not certain. It may generate nitric oxide or act via other smooth muscle–relaxing properties. The peak effect occurs approximately 3-5 hours after administration, and the duration of effect on blood vessels is approximately 12 hours.
Hydralazine is used to dilate arterioles and decrease cardiac afterload. It is primarily used for treatment of CHF, valvular disease of the heart, and other cardiovascular disorders characterized by high peripheral vascular resistance. It may be used with other cardiac drugs. Use in animals has been primarily derived from empirical use. There are no well-controlled clinical studies or efficacy trials to document clinical effectiveness. However, its use is not as common as other vasodilator drugs, such as the angiotensin-converting enzyme (ACE) inhibitors.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
在精確產品/強度、物種、途徑、適應症、標準化重複血壓與標的器官評估、血容量/灌流、心腎狀態、全部降壓/利尿藥、目標血壓、複查計畫及獸醫授權完成前,封鎖計算與自動滴定。貓 oral/SC 來源有重大衝突,所有注射使用只限住院。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。