商品名：Fungizone (traditional formulation) and liposomal
Antifungal drug. Amphotericin B is a fungicidal agent for systemic fungi. Amphotericin B binds to ergosterol in the fungal cell membrane, producing a loss of membrane integrity, leakiness, and cell death. Amphotericin is active against most fungi and some protozoa. There is a conventional formulation of amphotericin B deoxycholate that has been used most often in veterinary medicine. It is the least expensive but the most toxic. Lipid formulations of amphotericin B are now available. They are widely used in people but have not gained widespread use in veterinary medicine because of their high
Amphotericin B is indicated in patients with a variety of systemic mycoses. It is used to treat blastomycosis, coccidioidomycosis, and histoplasmosis. It also has been used to treat leishmaniasis in dogs. It may be administered for treatment of aspergillosis, but this is not a common use in veterinary medicine and some species of Aspergillus are resistant.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認確切劑型、商品、濃度、活性成分基準、保存狀態與相容性 確認物種、個體病史、診斷、感染部位、菌種、藥敏與免疫狀態 建立腎臟、電解質、肝臟、血液、心肺與反應監測及救援計畫 逐項審查共同用藥、院內處理、法域、食用動物殘留與停藥責任
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。