Ethacrynic acid reduces the absorption of electrolytes in the ascending section of the loop of Henle, decreases the reabsorption of both sodium (to a much greater extent than the thiazides) and chloride, increases the excretion of potassium in the distal renal tubule, and directly effects electrolyte transport in the proximal tubule. The exact mechanisms of ethacrynic acid’s effects have not been established. It has no effect on carbonic anhydrase nor does it antagonize aldosterone. Ethacrynic acid increases renal excretion of water, sodium, potassium, chloride, calcium, magnesium, hydrogen, ammonium, and bicarbonate.
In combination with other antimycobacterial drugs, ethambutol may be useful in treating mycobacterial infections caused by _M. bo-_ _vis_, _M. tuberculosis_, _M_ . _genavense_, _M. avium-intracellulare_ complex (MAC) in dogs or cats, particularly when the organism is resistant to treatment with other drug combinations (rifampin, enrofloxacin, azithromycin). In birds, ethambutol has been used in combination with other agents for treating mycobacterial ( _e.g_ ., _M. avium_ ) infections. Because of public health risks, particularly in the face of increased populations of immunocompromised people, treatment of mycobacterial ( _M. bovis_, _M. tuberculosis_, etc.) infections in domestic or captive animals is controversial.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
核對依他尼酸或依他尼酸鈉的精確身分、鹽型與完整成品 核對動物種類、病患狀態、腎功能、體液與電解質風險及聽力風險 核對所有同時用藥，特別是具耳毒性、抗凝血、鋰、利尿或影響體液電解質之藥物 核對法域、最新標示、核准與實際可取得狀態；人用標示不得替代獸醫契約
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。