商品名：Nizoral
Azole (imidazole) antifungal drug. Ketoconazole has a similar mechanism of action as other azole antifungal agents (itraconazole and fluconazole). It inhibits a P450 enzyme in fungi and inhibits ergosterol synthesis in fungal cell membrane. 414 Ketoconazole Fungistatic. It has antifungal activity against dermatophytes and a variety of systemic fungi, such as Histoplasma, Blastomyces, and Coccidioides and Malassezia yeast. Other azole antifungal drugs include voriconazole, itraconazole, and fluconazole.
Ketoconazole is used in dogs, cats, and some exotic animals to treat dermatophytes and systemic fungi, such as Blastomyces, Histoplasma, and Coccidioides. It also has been shown effective for treatment of Malassezia dermatitis. It does not have good activity against Aspergillus. Ketoconazole should not be used in horses because oral absorption is poor unless administered with a highly acidic vehicle. In dogs, it has a profound effect on cytochrome P450 enzymes and will inhibit metabolism of many drugs. This property has been used to reduce doses of cyclosporine (ketoconazole dose of 5-10 mg/kg
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認動物種類與更細分類、體重與年齡、繁殖狀態、精確診斷、病原與感染部位。 確認精確產品、規格、法域核准或調劑狀態，以及肝臟、內分泌與胃腸基線。 核對所有併用藥與補充品，設定個別監測、療效判定、停止與緊急處置條件。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。