商品名：Heartguard, Ivomec, Eqvalan liquid, Equimectrin,
Antiparasitic drug. Avermectins (ivermectin-like drugs) and milbemycins (milbemycin and moxidectin) are macrocyclic lactones and share similarities, including mechanism of action. These drugs are neurotoxic to parasites by potentiating glutamate-gated chloride ion channels in parasites. Paralysis and death of the parasite are caused by increased permeability to chloride ions and hyperpolarization of nerve cells. These drugs also potentiate other chloride channels, including ones gated by GABA. Mammals ordinarily are not affected because they lack glutamate-gated chloride Ivermectin 405 I chann
Ivermectin is used in horses for the treatment and control of large strongyles (adult) (Strongylus vulgaris, Strongylus edentatus, and Triodontophorus species), small strongyles (adult and fourth stage larvae) (Cyathostomum species, Cylicocyclus species, Cylicostephanus species), pinworms (adult and fourth-stage larvae) (Oxyuris equi), large roundworms (adult) (Parascaris equorum), hairworms (adult) (Trichostrongylus axei), large mouth stomach worms (adult) (Habronema muscae), neck threadworms (microfilariae) (Onchocerca species), and stomach bots (Gastrophilus species). In cattle it is used f
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
先確認 ivermectin 親成分與精確成品、單方或複方、濃度、劑型、法域與有效標示，排除其他 macrocyclic lactone、其他物種成品及調劑品互換。 再確認物種與個體、體重、年齡、診斷、寄生蟲與生命期、預防或治療目的、感染與檢測狀態、ABCB1 與其他易感因素、器官狀態、繁殖狀態及全部併用品。 由獸醫師建立個案成品、途徑、方案、終點、療效、安全、監測、停用、緊急處置、食物鏈、保存、丟棄與雙邊交互作用契約。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
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