商品名:Sublimaze and generic brands; Fentora buccal tablets
Synthetic opiate analgesic. Fentanyl is approximately 80 to 100 times more potent than morphine. Fentanyl is an agonist for the mu-opiate receptors on nerves and inhibits release of neurotransmitters involved with transmission of pain stimuli (such as Substance P). The central sedative and euphoric effects are related to mu-receptor effects in the brain. Fentanyl has a wide safety profile with doses as high as 300 times the recommended dose not being lethal in spontaneously breathing dogs. It is highly lipophilic—approximately 1000 times more lipophilic than morphine, which produces rapid diff
Fentanyl citrate is used as an intravenous bolus or as a constant rate infusion (CRI) in animals for relief of pain, an adjunct for anesthesia, or as a sedative in combination with other CNS sedatives. Fentanyl administered IV will produce Fentanyl Citrate 307 F antinociceptive effects for approximately 2 hours. Most of the doses are based on empiricism and experimental studies. Oral buccal tablets have been used in people for treatment of breakthrough pain, but there has been only anecdotal experience with this use in animals. See Fentanyl, Transdermal for information about transdermal form.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
未逐項確認精確注射產品、以 fentanyl base 計的濃度、物種、體重、途徑、適應症/程序、bolus 或 CRI、共同麻醉/鴉片計畫、病患風險、稀釋/pump、氣道、氧氣、輔助或控制通氣、拮抗劑及連續恢復監測前,不得計算或產生處方。口頰、貼片、兔與雪貂內容全部隔離。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。