商品名:Tylenol and generic brands
Analgesic drug. Exact mechanism of action is not known; however, acetaminophen probably inhibits centrally mediated pain transmission. The centrally mediated analgesia may occur via inhibition of COX-3, a variant of COX-1 found in the central nervous system. Other evidence indicates that acetaminophen may inhibit prostaglandins in some cells and tissue in which low concentrations of arachidonic acid are present. The site of acetaminophen action may be the peroxidase enzyme component of prostaglandin H2 synthase. Therefore, COX inhibition may occur at site-specific tissues, sparing the gastrointestinal mucosa, platelets, and kidneys but acting centrally. Other evidence suggests that acetaminophen can stimulate inhibitory pain pathways mediated by serotonin (5-HT3). This evidence suggests th
Acetaminophen is used as an analgesic and for pain control in dogs. Do not use in cats. It is considered relatively weak as an analgesic. Often used in combination with an opiate (e.g., codeine).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
貓無治療用途且任何暴露均為急診。犬僅能由獸醫依產品、疼痛情境、療程與肝腎風險個別決定;公開療效證據有限且矛盾,複方標籤不可套用單方。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。