商品名：Mylepsin, Neurosyn, and Mysoline (in Canada)
Anticonvulsant. Primidone is converted to phenylethylmalonamide (PEMA) and phenobarbital, both of which have anticonvulsant activity, but most of the activity (85%) is probably because of the phenobarbital. Phenobarbital acts to potentiate the inhibitory effects of GABA-mediated chloride channels. Primidone 649 P
Primidone is used for treating seizure disorders in animals, including epilepsy. The effects of primidone are primarily produced by the presence of the active metabolite, phenobarbital. Although it is possible that some patients with epilepsy that are refractory to phenobarbital alone will respond better to primidone, the number of such cases is low. Primidone is approved for use in dogs, but its use has declined in favor of administration of phenobarbital, bromide, or other anticonvulsants.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現行獸醫指引不建議使用 primidone；犬舊資料的 mg/kg/day 是日總量，不能變成每次量，貓則因毒性硬性排除。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。