商品名:Tranxene and generic
Benzodiazepine. Clorazepate is one of the active metabolites of diazepam, producing similar effects as diazepam but longer acting. After oral absorption it is quickly converted to the active drug, referred to as nordiazepam or desmethyldiazepam. Similar to diazepam and other benzodiazepines, its action is to enhance inhibitory effects of GABA in the central nervous system.
Clorazepate is used for antiseizure action, sedation, and treatment of some behavioral disorders. It has been used in dogs and cats when other drugs are not effective. It has been used in refractory epileptics, but tolerance may develop to the anticonvulsant effects with long-term use.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須由獸醫師確認氯氮卓二鉀的精確產品、鹽基準與賦形劑、管制法域、物種、診斷、叢發急救或維持情境、途徑、既往苯二氮平曝露與耐受、停藥風險、肝腎與呼吸狀態、懷孕泌乳、苯巴比妥及所有併用藥、監測與安全停藥計畫;任一條件未閉合均不得產生劑量、處方或自動交互作用結論。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。