商品名：Valium and generic brands
Benzodiazepine. Central acting CNS depressant. Mechanism of action appears to be via potentiation of GABA-receptor–mediated effects in CNS because it binds to the GABA binding site. Diazepam is metabolized to desmethyldiazepam (nordiazepam) and oxazepam. These metabolites also have some centrally acting benzodiazepine effects. In dogs, the intravenous half-life of diazepam is short (<1 hour), but active metabolites are produced. In cats, the intravenous half-life is approximately 5 hours.
Diazepam is used for sedation, anesthetic adjunct, anticonvulsant, and behavioral disorders. Although it is used as a muscle relaxant, its efficacy for this use is not established. In cats, diazepam has been administered IV for short-term stimulation of appetite. In cats, oral administration has been effective for decreasing urine spraying, but relapses are common when the drug is discontinued. Diazepam is usually administered orally or IV. However, it has been shown to be absorbed adequately in dogs from rectal administration and intranasal administration (41% absorption from nasal spray in d
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
急性癲癇、肌痙攣、鎮靜／麻醉、犬 rectal rescue、貓短期 IV 與貓高風險口服不可攤平。封鎖通用計算、處方與飼主劑量，尤其禁止貓反覆口服。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。