商品名：Ativan and generic brands
Benzodiazepine. Central-acting CNS depressant, with action similar to diazepam. Mechanism of action appears to be via potentiation of GABA receptor–mediated effects in CNS. In animals, lorazepam does not undergo extensive hepatic metabolism, but it is glucuronidated before excretion. In dogs, lorazepam had a half-life of 0.9 hours, with systemic clearance less than half that of diazepam. Oral absorption is 60%. Therefore, the oral formulation may be suitable in dogs for some conditions.
Lorazepam, as a benzodiazepine, may be considered for anxiety disorders in animals, but it has not been used as commonly as other drugs such as diazepam. Lorazepam also is effective for treating seizures, but it is not used as often in animals as other anticonvulsants. In controlled studies it has been equally as effective as diazepam in dogs. Losartan 443 L Instructions for Use Doses based on empiricism. There have been no clinical trials in veterinary medicine, although it is expected to produce effects similar to other benzodiazepines. For intravenous use, dilute 50/50 with 0.9% saline or 5
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認 lorazepam 活性分子、精確成品、劑型、強度、濃度、賦形劑、製造商、批次、完整性、來源、法域與目前管制及核准狀態。 確認物種、品種、年齡、體重、生理與繁殖狀態、診斷、癲癇型態、疾病嚴重度、共病、肝腎功能、呼吸循環與神經狀態。 依精確情境核對用量基礎、途徑、頻率、療程、速率、重複給藥、累積上限、監測、救援、停止與轉診計畫。 逐一核對所有藥物、補充品、酒精或可能誤食，尤其 opioid、鎮靜、麻醉、抗痙攣及其他中樞神經作用物質。 若有持續抽搐、呼吸困難、無法喚醒、倒下、反常興奮或疑似過量，立即由獸醫急診評估；不得依本資料自行救援。 逐一人工裁決藥對；受保護 peer 不得由對側 none、evaluated 或 override 解除。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
90%
1 hours