商品名：Daraprim
Antibacterial and antiprotozoal drug. Pyrimethamine blocks the dihydrofolate reductase enzyme, which inhibits synthesis of reduced folate and nucleic acids. Activity of pyrimethamine is more specific against protozoa than bacteria. Pyrimethamine is often combined with a sulfonamide to produce a synergistic effect.
Pyrimethamine is used to treat protozoal infections in animals. It is most often combined with a sulfonamide, either separately, or in a combined formulation. See pyrimethamine + sulfadiazine monograph for additional information.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
Pyrimethamine 的公開獸醫方案受確切複方、物種、適應症、療程與骨髓監測限制；通用範圍會把不同療程及不完整證據混算，且錯誤調製濃度曾造成馬死亡。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
56%
3-4 hours