商品名:Clincox
Coccidiostat. Diclazuril is a triazinone antiprotozoal that is effective for treating infections caused by Isospora spp., Toxoplasma gondii, and Eimeria spp. and has been used for treating coccidiosis. It also has been used in horses to treat equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. Toltrazuril sulfone (ponazuril) is an active metabolite found in serum and cerebrospinal fluid (CSF) of treated horses. Because of the availability of a commercial formulation of ponazuril (Marquis), it is preferred over diclazuril by many veterinarians for treating infections in horses.
Dosage information for diclazuril has been based on approved indications, experimental studies, pharmacokinetic data, and limited clinical experience. Diclazuril has been replaced by ponazuril for treating most cases of EPM in horses.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
先核對活性成分、完整產品名稱、濃度、劑型、標示版本、法域與核准狀態 分開馬 EPM、禽類藥物飼料、反芻動物口服懸液、犬貓 off-label 與研究物種 食用動物逐一核對現行 medicated-feed 法規、MRL、withdrawal、產蛋與繁殖限制 保留 field-study 分母、對照、事件與因果歸因,不把未歸因事件排成通用副作用頻率 不把 high-exposure tolerance 轉成 regimen 或無風險保證 不接受 clazuril、toltrazuril、ponazuril、MARQUIS 或任何 metabolite payload
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)