商品名：Navigator (horse preparation) and Alinia (human
Antiprotozoal drug. Nitazoxanide (NTZ) is a nitrothiazolyl-salicylamide derivative. Its action against protozoa is unknown, but it may be related to the inhibition of the pyruvate-ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction essential to anaerobic and protozoal energy metabolism. Activity has been demonstrated against a variety of protozoa, including Cryptosporidium parvum, Giardia, Isospora, and Entamoeba. It also has activity against intestinal helminths, such as Ascaris, Ancylostoma, Trichuris, and Taenia. It also may be active against some anaerobic bacteria, including Helicobacter. One of the active metabolites is tizoxanide.
Nitazoxanide (NTZ) is used to treat equine protozoal myeloencephalitis (EPM). It has had only limited use in other veterinary species, but there is a form approved for use in people for treatment of protozoal infections, such as C. parvum and Giardia. There has been only limited use in dogs and cats for intestinal protozoal infections but no reports to document efficacy and safety.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
Navigator 已於 2009 年撤銷；馬劑量僅屬歷史資料，犬方案只是小型研究 exposure、不是驗證常規療程，亦未確認貓方案。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal