商品名:Prilosec (formerly Losec; human preparation),
Proton pump inhibitor (PPI). Omeprazole inhibits gastric acid secretion by inhibiting the K+/H+ pump (potassium pump). Omeprazole is more potent and longer acting than most available antisecretory drugs. Other proton pump inhibitors include pantoprazole (Protonix), lansoprazole (Prevacid), and rabeprazole (Aciphex). They all act via similar mechanism and are equally effective. PPIs also have some effect for inhibiting Helicobacter organisms in the stomach when administered with antibiotics. Omeprazole is decomposed in the acid environment of the stomach. Oral absorption is decreased if adminis
Omeprazole, like other PPIs, is used for treatment and prevention of GI ulcers. It has been used in dogs, cats, and exotic species, but most efficacy data for animals have been produced in horses, in which it has been shown that omeprazole is effective for treating and preventing gastric ulcers. In foals, 4 mg/kg q24h suppressed acid secretion for 22 hours (by comparison, ranitidine suppressed acid up to 8 hours at a dose of 6.6 mg/kg). In dogs, 1 mg/kg q24h PO is as effective as pantoprazole (1 mg/kg) and famotidine (0.5 mg/kg q12h) for maintaining stomach pH >3-4. Repeated doses may be neces
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
犬貓參考與健康動物酸度研究不能建立單一通用方案;三個馬用標籤的治療、防復發與壓力期預防療程/刻度又各不相同。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
1 hours