商品名：Protonix
Proton pump inhibitor (PPI). Pantoprazole inhibits gastric acid secretion by inhibiting the K+/H+ pump. Pantoprazole, like other PPIs, has potent and long- acting effects. Acid suppression may have a duration >24 hours in animals. Other PPIs that are administered orally (e.g., omeprazole) have been used in animals. Pantoprazole is the first PPI that can be administered IV. After a dose, it inhibits acid secretion for >24 hours.
Pantoprazole is used for treatment and prevention of GI ulcers. Other PPIs include omeprazole, lansoprazole (Prevacid), and rabeprazole (AcipHex). All PPIs act via a similar mechanism and are equally effective. However, there has been more experience with omeprazole in animals than the other drugs of this group. In dogs, pantoprazole (1 mg/kg) maintained stomach pH >3-4 when administered IV. Pantoprazole, being the only one in an IV formulation, is often used when an intravenous drug is preferred for treatment. Pantoprazole 583 P Instructions for Use For treating GI ulcers, administer once per
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現有服務無法區分健康動物 pH 研究與臨床病患、IV 與延遲釋放口服、neonatal foal 與一般 horse、alpaca SC 與其他物種，亦無食用動物殘留門檻。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
77%