商品名:Biaxin and generic brands
Macrolide antibiotic, with bacteriostatic activity. It is a substituted 14-carbon macrolide. Clarithromycin was introduced in 1990 as a substitute for erythromycin. Compared to erythromycin it has higher absorption, a longer half-life, and increased intracellular uptake. Site of action is similar to other macrolide antibiotics, which is the 50-S ribosomal subunit in susceptible bacteria. Spectrum includes primarily gram-positive bacteria. Resistance is expected for most gram-negative bacteria. Clarithromycin may have higher activity (lower MIC values) for many bacteria compared to erythromycin
Most common use in people is for treatment of Helicobacter gastritis and respiratory infections, where it has retained activity against most respiratory tract pathogens (e.g., Streptococcus, mycoplasma, chlamydia). In small animals, clarithromycin has been used for indications such as skin infections and respiratory infections. In foals, clarithromycin has been used for treatment of infections caused by Rhodococcus equi (in combination with rifampin) and produced better clinical success than azithromycin.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
執行前必須由獸醫師核對精確商品、釋放型態與濃度、物種與病患、感染部位、病原及菌株、培養與感受性、單用或複方、交互作用、肝腎與心律風險、監測、抗菌藥物管理及法域;公開證據不足以建立通用犬貓馬執行契約。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
4.8 hours