共 22 項交互作用,下方顯示按嚴重性排序的前 20 項
In humans, particularly with severe cardiomyopathy, cardiac arrest has occurred (rarely)
Flecainide⛔ 高風險
Possible additive effects; use is together with verapamil is to be avoided in humans
Verapamil may increase serum levels of theophylline and lead to toxicity
COPP Chemotherapy⚠️ 中風險
May decrease oral absorption of verapamil
Verapamil may increase levels
Verapamil may increase the blood levels of digoxin; monitoring of digoxin levels recommended
Verapamil may increase concentrations
May increase verapamil levels
By inhibiting P-gp may increase loperamide plasma concentrations
Neuromuscular blockers⚠️ 中風險
Neuromuscular blocking effects of nondepolarizing muscle relaxants may be enhanced by verapamil
Possible decreased clearance; increased elimination half-life of quinidine; increased risk for hypotension
Calcium channel blockers may increase intracellular vincristine by inhibiting the drug’s outflow from the cell
ACE Inhibitors✅ 低風險
May cause additive hypotensive effects
Alpha-adrenergic Blockers✅ 低風險
May cause additive hypotensive effects
Beta-adrenergic blockers✅ 低風險
May cause additive negative cardiac inotrope and chronotrope effects
Cardiovascular collapse reported in animals when used with verapamil
Because of additional negative inotropic effects, use of disopyramide within 48 hours of using verapamil is not recommended disopyramide phosphate 315
Diuretics✅ 低風險
May cause additive hypotensive effects
Has been associated with potentiating the anesthetic and respiratory depressant effects of etomidate Laboratory Considerations No specific laborato...
May reduce verapamil levels
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