商品名：Oncovin, Vincasar, and generic brands
Anticancer agent. Vincristine, like vinblastine, belongs to the vinca alkaloid group of anticancer agents. They have been called “spindle poisons” because they have an affinity for tubulin in cells. Tubulin is the protein that forms the microtubules responsible for chromosome migration during mitosis. Vinca alkaloids block polymerization of the cellular microtubules and therefore arrest mitosis in metaphase (m-phase specific). Vincristine has an affinity for the tubulin of platelets. For thrombocytopenia, vincristine increases thrombopoiesis, increases fragmentation of megakaryocytes, and decr
Vincristine is used in combination chemotherapy protocols. It is included in several anticancer chemotherapy protocols, usually with corticosteroids, alkylating agents, and other drugs. It has been used in veterinary medicine for lymphoreticular tumors, transmissible venereal tumors (TVT), mammary neoplasia in cats, and other solid tumors. It is a component of several combination protocols and may also be useful as a single agent for some tumors.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
長春新鹼為窄治療範圍、僅 IV、發泡性且具致命錯誤途徑風險的細胞毒性危害藥。TVT、犬／貓 CHOP 與犬 ITP 的數值、間隔、併藥及監測皆不同，不得攤平成通用計算器；自動計算、處方與飼主劑量均封鎖。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。