Bleomycin is an antibiotic that has activity against a variety of gramnegative and gram-positive bacteria as well as some fungi. While its cytotoxicity prevents it from being clinically useful as an antimicrobial, it can be useful against a variety of tumors in small animals. Bleomycin has both a DNA binding site and a site that binds to the ferrous form of iron. By accepting an electron from ferrous ion to an oxygen atom in the DNA strand, DNA is cleaved. Resistance to bleomycin therapy is via reduced cellular uptake of the drug, reduced ability to damage DNA and increased rates of DNA repair by the cell and, probably most importantly, via the enzyme bleomycin hydrolase.
Boldenone is labeled for use as adjunctive therapy “. . . as an aid for treating debilitated horses when an improvement in weight, haircoat, or general physical condition is desired” (Package Insert; _Equipoise_ ®—Fort Dodge). Boldenone may possibly be useful to stimulate appetite in cats.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
Bleomycin 的肺毒性與累積暴露、腎排除及麻醉氧暴露相互關聯；獸醫電化學治療又必須把腫瘤體積、途徑、藥物至電脈衝時間與設備參數一起閉合。現有專案同時混有 USP units、mg potency、IU、錯誤口服途徑、未公開確認的泛用犬貓療程與多種跨藥污染，因此任何數字都不能直接進入計算器或飼主介面。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
2 hours