商品名：Cytosar, Ara-C, and Cytosine arabinoside
Anticancer agent. Cytarabine (Cytosar) is a compound isolated from a sea sponge. It has also been referred to as cytosine arabinoside and Ara-C. Cytarabine is metabolized to an active drug that inhibits DNA synthesis. It was once thought that its action was via inhibition of the enzyme DNA polymerase, but the exact mechanism of action may not be known. The half-life in dogs is approximately 70 minutes.
Cytarabine has been used for lymphoma and leukemia protocols. The most common use of cytarabine is treatment of lymphoma and myelogenous leukemia. It is usually administered as an intramuscular or subcutaneous injection because it has a short half-life (approximately 20 minutes) when administered IV. It has also been administered to dogs for treatment of granulomatous meningoencephalomyelitis as an alternative to corticosteroids.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
同一總量會因診斷、route、輸注時間、分次、cycle、產品與合併藥產生不同暴露與毒性。犬 MUO、腫瘤與 intrathecal 方案不能壓成一個 mg/m² 答案；在 D0062／D0188 去重、精確產品／防腐劑／途徑、baseline CBC／器官功能、專科 protocol、雙人計算與 hazardous-drug controls 閉合前，封鎖計算、處方與飼主劑量。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal