商品名:Norpace (Rhythmodan in Canada)
Antiarrhythmic agent of Class I. Disopyramide blocks inward sodium channel and depresses myocardial electrophysiologic conduction rate.
Disopyramide is used for control of ventricular arrhythmias. Its use in veterinary medicine is not as common as for other drugs. Studies of efficacy in animals have not been reported. Dithiazanine Iodide 249 D Instructions for Use Disopyramide is not commonly used in veterinary medicine because of its short half-life in dogs. Other antiarrhythmic drugs are preferred. Patient Monitoring and Laboratory Tests Monitor ECG in treated animals. This drug can be proarrhythmogenic. Formulations Disopyramide is available in 100- and 150-mg capsules and 10-mg/mL injection (Canada only). Stability and Storage Store in a tightly sealed container, protected from light, and at room temperature. Compounded oral formulations have been stable for 30 days. Small Animal Dosage
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
沒有足夠公開臨床獸醫證據支持通用犬貓劑量;須由心臟專科確認物種、適應症、一般/控制釋放產品、ECG、收縮功能、腎肝功能、電解質與交互作用。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。