商品名：Imodium and generic brands
Opiate agonist. Like other opiates, loperamide acts on the mu-opiate receptors of the GI tract. It decreases propulsive intestinal contractions and increases segmentation (an overall constipating effect). It also increases the tone of GI sphincters. In addition to affecting motility, opiates have an antisecretory effect and stimulate absorption of fluid, electrolytes, and glucose. Their effects on secretory diarrhea are probably related to inhibition of calcium influx and decreased calmodulin activity. Action of loperamide is limited to the intestine. CNS effects do not occur because it does n
Loperamide is used for symptomatic treatment of acute nonspecific diarrhea. It has been administered orally to dogs and cats. Long-term use is discouraged because it may lead to constipation. It has been administered to large animals, but this is not recommended.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認確切鹽類、單方或複方產品、劑型、強度、濃度、賦形劑、批號、完整性、來源、管轄區與目前監管狀態。 確認物種、品種、個體 ABCB1 基因結果、年齡、體重、生理狀態、妊娠、哺乳、繁殖與食用動物用途。 確認腹瀉病因、急慢性、嚴重度、糞便出血、腸阻塞、感染、胰臟或其他原發病、水合、電解質及肝腎狀態。 依確切產品核對用量、間隔、路徑、療程、給藥與進食關係、共同照護、監測、停止條件、過量與轉診計畫。 逐一核對所有共同藥物、補充品與可能誤食，特別是影響腸運動、鈣離子通道、代謝、轉運、阿片或中樞神經的藥物。 逐一人工裁決藥對；受保護同儕不得由對側 none、evaluated 或 override 解除。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
11 hours