商品名:Adalat and Procardia
Calcium-channel blocking drug of the dihydropyridine class. Vasodilator. The action of nifedipine is similar to other calcium-channel blocking drugs, such as amlodipine. They block voltage-dependent calcium entry into smooth muscle cells. Drugs of the dihydropyridine class are more specific for vascular smooth muscle than the cardiac tissue. Therefore, they have less effect on cardiac conduction than diltiazem.
Nifedipine is used for smooth muscle relaxation and to induce vasodilation. It is indicated for treatment of systemic hypertension. Use in animals is rare because there is more experience with amlodipine. The use of nifedipine in animals has been primarily derived from empirical use. There are no well-controlled clinical studies or efficacy trials to document clinical effectiveness.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
未確認犬、貓或馬可直接使用的公開臨床 nifedipine 劑量。現有貓劑量含 macrocrystalline/泌尿道抗菌療程式跨藥污染,馬疝痛內容只有離體研究;實驗犬貓曝露也不是處方。封鎖計算器、處方與飼主劑量。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。