商品名:Versed
Benzodiazepine. Central-acting CNS depressant. Midazolam, like other benzodiazepines, binds to a specific GABA-binding site. It may modify the GABA- binding sites and increase the action of GABA on nerve cells. Sedative effects of midazolam may be attributed to potentiation of GABA pathways that act to regulate release of monoamine neurotransmitters in the CNS. Benzodiazepines may act as muscle relaxants by inhibiting certain spinal pathways or directly depressing motor nerve and muscle function.
Midazolam is used as an anesthetic adjunct. It is used for similar indications as diazepam, but because it is water soluble, midazolam can be administered in an 510 Midazolam Hydrochloride aqueous vehicle and administered IM compared to other drugs of this class (drugs such as diazepam are not water soluble). It has been used as an anticonvulsant, muscle relaxant, sedative, and adjunct with anesthetic agents. In foals, it has been used to treat neonatal seizures (see dose protocols).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
鎮靜、共同誘導、癲癇救援、CRI、物種、route、濃度、合併藥與 airway 能力不可攤平成通用計算;鳥類劑量未確認,貓 route 證據也不能直接套犬。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。