商品名:Norvasc
Calcium-channel blocking drug. Amlodipine is a calcium-channel blocker of the dihydropyridine class. It decreases calcium influx in cardiac and vascular smooth muscle. Its greatest effect is on vascular smooth muscle, acting as a vasodilator. Hypertension in cats has been defined as systolic blood pressure >190 mm Hg and diastolic pressure >120 mm Hg.
In cats and dogs it is used to treat systemic hypertension (high blood pressure). Amlodipine is considered the drug of choice by many clinicians for treating hypertension in cats. By comparison, angiotensin-converting enzyme (ACE) inhibitors are less effective in cats. Amlodipine may improve survival in cats with hypertensive kidney disease. In cats, addition of a beta blocker to slow heart rate may also be beneficial.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現行服務無法強制產品/法域/體重、持續性高血壓或急性 TOD、14 日 SBP 調整及犬 RAAS 共治療門檻,因此封鎖通用計算與處方。美國 AMODIP 標示為貓 q24h,治療 14 日後才依 SBP 決定是否提高;低於 2.5 kg 無法用該產品準確給藥。犬範圍只能作指引脈絡,不能與心衰或單方 CKD 混成自動答案。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
35 hours