Oral Medications⛔ 高風險
Because oral sodium bicarbonate can either increase or reduce the rate and/or extent of absorption of many orally administered drugs, it is recomme...
The solubility of ciprofloxacin and enrofloxacin is decreased in an alkaline environment; patients with alkaline urine should be monitored for sign...
When urine is alkalinized by sodium bicarbonate, excretion may be decreased
When urine is alkalinized by sodium bicarbonate, excretion may be decreased
Salicylates⚠️ 中風險
When urine is alkalinized by sodium bicarbonate, excretion of weakly acidic drugs may be increased
Azole Antifungals✅ 低風險
Concomitant oral sodium bicarbonate may reduce absorption; administer separately
Corticosteroids✅ 低風險
Patients receiving high dosages of sodium bicarbonate and ACTH or glucocorticoids may develop hypernatremia
Diuretics✅ 低風險
Concurrent use of sodium bicarbonate in patients receiving potassium-wasting diuretics may cause hypochloremic alkalosis
Histamine2 [blocking agents][✅ 低風險
Con-] comitant oral sodium bicarbonate may reduce absorption; administer separately
Oral sodium bicarbonate may reduce the efficacy of sucralfate if administered concurrently
Concomitant oral sodium bicarbonate may reduce absorption; administer separately
anticholinergic agents✅ 低風險
Concomitant oral sodium bicarbonate may reduce absorption; administer separately
iron products✅ 低風險
Concomitant oral sodium bicarbonate may reduce absorption; administer separately