商品名：Methenamine hippurate: Hiprex and Urex;
Methenamine is a urinary antiseptic. Methenamine in the acid environment of the urine is hydrolyzed to formaldehyde and ammonia to produce an antibacterial/ antifungal effect. A low urine pH of at least 5.5 or less is needed for optimal effect. If this can be achieved, it is active against a wide range of bacteria, and resistance does not develop. It is less effective against Proteus species that produce an alkaline Drug Interactions Use cautiously with other treatments that could cause metabolic acidosis. Methenamine 487 M urine pH. Because there is no systemic absorption, it is not effective for systemic infections. Absorption is rapid and produces a peak effect in urine at 0.5-1.5 hours and has a half-life of 3-6 hours.
Methenamine is used as a urinary antiseptic. There is a lack of well-controlled clinical trials to show its effectiveness. However, it has been used in animals to prevent recurrences of lower UTIs. It is probably less effective for treating ongoing infections. It is critical that the urine pH is low for conversion to formaldehyde.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
核對 methenamine 的精確鹽類、商品、全部活性成分、賦形劑與法域狀態。 分開散發性膀胱炎、復發性膀胱炎、腎盂腎炎、前列腺炎、無症狀菌尿、導尿管相關疾病與非感染性泌尿症狀。 依個案評估臨床症狀、尿液培養與藥物感受性、腎肝功能、水合、尿液酸鹼環境、共病與其他藥物。 在完整的反應、停止、監測與救援契約未閉合前，不產生劑量、處方或自動交互作用。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。