商品名:Intropin
Adrenergic and dopamine agonist. Dopamine is a neurotransmitter and an immediate precursor to norepinephrine. At low doses it stimulates the dopamine (DA1) receptors, at moderate doses it stimulates the adrenergic receptors, and at high doses it acts as an alpha1-receptor agonist (producing vasoconstriction). At doses that stimulate DA1 receptors, it increases c-AMP in smooth muscle cells and causes relaxation and vasodilation. It has been administered to stimulate the heart and to increase urine flow (see below for explanation of renal effects).
Dopamine is used therapeutically to stimulate myocardium via action on cardiac beta1-receptors. Dopamine infusions will increase both blood pressure and cardiac output. These effects are caused by stimulating cardiac contractility and heart rate by acting as an agonist for beta1-adrenergic receptors. In addition, dopamine increases the release of norepinephrine from nerve terminals (dopamine is a precursor for norepinephrine). It produces a greater chronotropic effect than dobutamine. It has been proposed that dopamine dilates renal arterioles, increases renal blood flow, and increases the glo
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
Dopamine 是院內高警訊持續 IV infusion。必須確認物種、休克/正性肌力目標、容量、酸鹼與氧合、精確產品、原液/最終濃度、相容性、大靜脈、pump、滴定終點、連續血流動力/外滲監測及逐步停藥;低劑量不得用於犬貓 AKI 腎臟保護。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
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