商品名:Larodopa and L-dopa
Dopamine, when administered systemically, does not cross the blood–brain barrier. However, levodopa crosses more easily via a carrier-mediated process and is converted to dopamine after crossing the blood–brain barrier. Dopamine is used in neurodegenerative disorders to stimulate CNS dopamine receptors.
In people, levodopa is used for treating Parkinson’s disease, and it is used in combination with carbidopa (a peripheral decarboxylase inhibitor) and entacapone (an o-methyltransferase inhibitor) to potentiate therapy. In animals, it has been used for treating hepatic encephalopathy.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
D0382 只保留精確產品、人類或犬隻實驗情境綁定的不可執行證據。犬、貓、兔及所有其他物種均不得由目前介面取得劑量、處方或自動交互作用結論。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。