商品名:Enterocort
Budesonide is a locally acting corticosteroid but is 1000 times more active than prednisolone as a corticosteroid. It is approved for use in people, but there has been only limited use in small animals. Budesonide granules are contained in an ethylcellulose matrix that is coated with methacrylic acid polymer. This coating does not release the drug until the pH is >5.5. Therefore, the drug is not usually released until it reaches the distal GI tract. If any is absorbed, 80%-90% is inactivated by metabolism first-pass effects. Therefore, systemic glucocorticoid effects are minimized. In humans i
In animals it has been used to treat inflammatory bowel disease. The most common use has been for treating colitis in dogs or inflammatory bowel disease in cats. There is only limited experience with budesonide in dogs and cats, and reports of successful treatment are mostly anecdotal.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認精確產品、劑型、釋放系統或吸入裝置、動物種類、診斷與治療階段 確認既往與目前的類固醇暴露、是否需轉換或漸減,以及感染、肝功能、內分泌與眼部風險 逐一人工審查所有合併藥物,特別是可能影響 CYP3A 的藥物;不得從人用標示自動生成獸醫交互作用 建立病患專屬的療效、HPA 軸與其他風險監測以及緊急聯絡計畫
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
10%
2 hours
fecal