商品名：Lomotil
Opiate agonist. Binds to mu-opiate receptors in intestine and stimulates smooth muscle segmentation in intestine, decreases peristalsis, and enhances fluid and electrolyte absorption.
Diphenoxylate is used for acute treatment of nonspecific diarrhea. It has primarily a local effect. Loperamide (Imodium) has a similar action and has become more popular for this indication. An additional use, not often used in veterinary medicine, is as an antitussive. Dipyridamole 245 D Instructions for Use Doses are based primarily on empiricism or extrapolation of human dose. Clinical studies have not been performed in animals. Diphenoxylate contains atropine, but the dose is not high enough for significant systemic effects. Patient Monitoring and Laboratory Tests No specific monitoring is necessary. Formulations Diphenoxylate is available in 2.5-mg tablets. Stability and Storage Store in a tightly sealed container, protected from light, and at room temperature. Stability of compounded
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認精確產品、兩種有效成分、鹽型、有效基團當量、單位含量、劑型、製造或標示者、核准狀態與司法管轄 確認物種、體重、年齡、腹瀉病因、感染與毒素風險、阻塞與腸蠕動狀態、脫水與電解質狀態、肝腎功能、繁殖狀態及全部併用藥 由獸醫師建立補液與病因處理、意識與呼吸、腹部脹大、排便、心率、體溫、泌尿與阿托品效應的監測與升級處置計畫 確認管制藥品保存、誤食與過量通報、專業急救、剩藥與廢棄物流程
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。