商品名：5-aminosalicylic acid, Asacol, Mesasal, Pentasa, and
Mesalamine is also known as 5-aminosalicylic acid. It is the active component of sulfasalazine, which is commonly administered for treatment of colitis. (See sulfasalazine and olsalazine for additional information.) The action of mesalamine is not precisely known, but it appears to suppress the metabolism of arachidonic acid in the intestine. It inhibits both cyclo-oxygenase and lipoxygenase-mediated mucosal inflammation. Systemic absorption is low; most of the action is believed to be local. There are four formulations of mesalamine used: 1. Asacol. Asacol is a tablet coated with an acrylic-based resin. The resin dissolves at a pH of 7.0 and is designed to release 5-aminosalicylic acid in the colon. 2. Mesasal. Mesasal is a tablet coated with an acrylic-based resin that dissolves at a pH
Mesalamine is used for treatment of inflammatory bowel disease, including colitis in animals. Most often sulfasalazine is used; however, in some animals, especially those sensitive to sulfonamides, mesalamine may be indicated. Use in animals has been primarily derived from empirical use. There are no well-controlled clinical studies or efficacy trials to document clinical effectiveness.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
只保留精確產品、研究設計與物種明確的不可執行證據。犬、貓與其他物種均不得由現有介面取得劑量、處方、自動交互作用結論或發生率分層。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。